ABOUT SIS®
Learn about small intestinal submucosa. The magic behind the FISH™ Device.
View the device in action. Learn procedure steps and techniques.
Educate yourself on post procedure care and cautions.
Schedule an intro,
in-service or request for information.
Extracellular Matrix
SIS® is a naturally occurring form of extracellular matrix or ECM.
ECM is a bioscaffold that surrounds cells in almost all tissues and organ structures. ECM has both structural and functional roles, and while the composition of the ECM varies by tissue, it is generally composed of four major types of molecules:
Structural Proteins
Collagen and Elastin
Adhesion Glycoproteins
Fibronectin and Laminin
Glycosaminoglycans (GAGs)
and Proteoglycans
Hyaluronan, Heparin Sulfate, Heparin and Dermatan Sulfate
Matricellular Proteins Thrombospondins, Osteopontin
and Tenascins
All rights reserved. Morris Innovative, Inc. 2010