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SIS® - Small Intestinal Submucosa

Origin

Naturally Occuring -
The Similarities Between Human Tissue & SIS®


Extracellular Matrix


Where It Is Used

Clinical References

SIS® in the Media
Naturally Occurring - SIS®
SIS® and FISH™ provide ingredients found in the body's natural tissue. Note the similarities found between human tissue and SIS® below.
Collagen Matrix: Type I, III, IV & VI
Provides cell guidance and migration, while providing structure and support to the matrix.

Elastin: Contributes to tissue elasticity.

Glycosaminoglycans: Heparin Sulfate, Hyaluronic Acid, Chondroitan: Binds growth factors, maintains moisture, decreases inflammation and promotes cell adhesion as well as proliferation.

Glycoproteins: Fibronectin, Laminin (c)
Promotes cell proliferation, migration and attachment.

Proteoglycans: Decorin, HSPG
Regulates collagen fibril structure, cell migration, binds growth factors and promotes angiogenisus.

Growth Factors: FGF-2, TGF-βI, CTGF
Promotes angiogenisus, cell activation and migration

All rights reserved. Morris Innovative, Inc. 2010