Learn about small intestinal submucosa. The magic behind the FISH™ Device.
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SIS® Origin
SIS tissue repair products are biologic grafts harvested from porcine small intestinal submucosa (SIS).
The submucosa is located between the mucosal and muscular layers of the small intestine. In addition to being a repository for growth factors, the submucosal layer provides strength to the small intestine through a complex organization of collagen that forms a fibrous matrix.
SIS products are extracted from the intestine in a manner that removes all cells, but leaves the complex extracellular matrix intact. The careful processing leaves the naturally fibrous and porous nature of the matrix available for new cell ingrowth.
All rights reserved. Morris Innovative, Inc. 2010
